AIM:To evaluate the efficacy and safety of posterior chamber phakic intraocular lens implantation for the correction of high myopia by ultrasound biomicroscopy(UBM)and optical coherence tomography(OCT).

METHODS:Twenty-four high myopia patients(48 eyes)who underwent the implantation of implantable collamer lens(ICL)or toric implantable collamer lens(TICL)in our hospital from Jan. 2015 to Apr. 2015 were observed. The various data included central anterior chamber depth(ACD); angle opening distance 500(AOD500); the distance between crystal lens and IOL(ICL-vault); postoperative best corrected visual acuity(postoperative-BCVA); postoperative uncorrected visual acuity(postoperative-UCVA); counts of endothelial cells; intraocular pressure(IOP); break-up time(BUT)by slit lamp were investigated during 1mo, 3mo, 6mo and 1y respectively on postoperative check while compared with the data of preoperation. The data were analyzed.

RESULTS:UBM were used to investigate ACD and four directions of AOD500 in 1mo, 3mo, 6mo and 1y postoperative. The results were all reduced compared with preoperation. The differences were statistically significant(P<0.05). After the distances between crystal lens and IOL being examined by OCT after operation, we found that the four time nodes were not statistically different(P>0.05). However, all results including postoperative best corrected visual acuity(postoperative-BCVA), postoperative uncorrected visual acuity(postoperative-UCVA)were improved compared with preoperation. There was significant difference between preoperation and postoperation(P<0.05). However, there was no significant difference in the various time points postoperative. Besides, there was no significant difference in mean IOP, mean counts of endothelial cells and the average BUT between preoperation and 4 times of postoperative following up studies(P>0.05).

CONCLUSION:Several clinical data have proved curative effect and safety of ICL implantation for the correction of high myopia. The stability of tear film has no obvious change. The patients are highly satisfactory.