AIM: To explore the clinical effect of capsule membrane phacoemulsification and capsular bag in phacoemulsification in treatment of hard nuclear cataract with high myopia.

METHODS: A total of 297 patients(322 eyes)with hard nucleus cataract(Ⅳ-Ⅴ grade nucleus)and high myopia were selected from Mar.2014 to Mar.2016 in our hospital. They were randomly divided into the observation group with 149 cases(162 eyes)and the control group with 148 cases(160 eyes). The observation group received capsule membrane phacoemulsification and the control group received capsular bag in phacoemulsification. The therapeutic effect and safety of patients in two groups were compared. The comparison of phacoemulsification time, energy parameters and corneal endothelial cell density used t-test, post-operative visual acuity and the occurrence of complications were tested by Chi-square test.

RESULTS: The harder the nucleus was, the longer the phacoemulsification time and higher the average phacoemulsification energy was, and the differences were statistically significant(P<0.05). The phacoemulsification time and energy parameters of the observation group were significantly lower than that of the control group(P<0.05). One month after operation, the postoperative visual acuity in two groups was significantly higher than the visual acuity at 1d after operation(P<0.05). But there was no statistical significance on the visual acuity at 1mo after operation between two groups(P>0.05). After operation, the density of corneal endothelial cell in two groups was significantly lower than the density before operation(P<0.05). But there was no statistical significance on the density of corneal endothelial cell after operation between two groups(P>0.05). The intraoperative complication rate of observation group was significantly lower than that of the control group(P<0.05), but there was no statistical significance on postoperative complication rate between two groups(P>0.05).

CONCLUSION: For the treatment of hard nuclear cataract with high myopia, capsule membrane phacoemulsification and capsular bag in phacoemulsification have similar effect, but capsule membrane phacoemulsification has better safety.