AIM: To explore the effect of comprehensive therapy in the treatment of fungal corneal ulcer and clinical outcome.

METHODS: A total of 159 cases 159 eyes fungal corneal ulcer patients took comprehensive therapy of 10 measures, followed up more than 3mo to observe the treatment effect and the final visual acuity in our hospital for treatment.

RESULTS: The average hospitalization time of fungal corneal ulcer was(12.11±5.13)d. A total of 148 cases of 148 eyes were cured, and the cure rate was 93.1%; improvement in 8 cases, accounted for 5.0%; 3 cases were ineffective, accounted for 1.9%. The final visual acuity of 89 eyes ≥0.3, accounted for 56.0%(89/159). The final visual acuity of 136 eyes ≥0.1, accounting for 85.5%(136/159), and accounting for 91.9% in 148 cured patients.

CONCLUSION: The comprehensive therapy in the treatment of fungal corneal ulcer has higher cure rate and visual acuity.