AIM: To discuss the effect of biochemical indexes on condition of middle aged and senior people with cataract.

METHODS: A total of 132 patients with cataract from Jan. 2014 to Jan. 2016 in our hospital were collected as the observation group. And 156 patients besides cataract were chosen as the control group. All entrants were divided into group A(40-59y), group B(60-79y)and group C(≥80y)according to the age. The biochemical indexes of all entrants were checked, including ALB, GLB, TP, GLU, BUN, UA, Cr, ALT, LDH, ALP, TC, Ca, Na, K and P. And all indicators were given phase relationship analysis.

RESULTS:There were no statistically significant in the level of ALP, ALT, K, P, LDH between observation group and control group. The level of ALB, GLB, TP, GLU, BUN, Cr, TC, Ca, Na in observation group were higher than those in the control group. The results of Logistic regression between two groups were as follow the level of ALB, GLU, BUN, Cr, Ca might be enrolled as risk factors for cataract. In group A, the level of ALB, GLU, Na in observation group were higher than those in the control group. In group B, the level of ALB, BUN, Cr, GLU, Na in observation group were higher than those in the control group. In group C, the level of BUN, Cr, GLU, Na in observation group were higher than those in the control group(P<0.05).

CONCLUSION: The level of ALB, TP, BUN, Cr, TC, Ca was significantly increased which suggested that those change might associate with the pathogenesis of cataract.