AIM:To explore the clinical effect of carboxymethylcellulose sodium eye drops and recombined human epidermal growth factor(rhEGF)on the cataract patients with dry eye after phacoemulsification.

METHODS: A total of 150 patients with cataract(150 eyes)referred to our hospital from Oct.2015 to May 2016 were randomly divided into trial group and control group, 75 cases in each group. All patients after cataract phacoemulsification were received the treatment of dry eye according to different groups. In treatment goup, patients were treated by carboxymethylcellulose sodium eye drops and rhEGF. In control group, patients were treated by carboxymethylcellulose sodium eye drops. The subjective dry eye symptoms, as well as fluorescein staining(FL), Schirmer Ⅰ test(SⅠt)and tear break-up time(BUT)were recorded before treatment, 1wk, 1mo after treatment.

RESULTS: Before treatment, there were no significant differences between groups in the subjective dry eye symptoms and the results of BUT, FL and SⅠt(P>0.05). After treatment, all the index in two groups significantly improved over time(P<0.01), and all the index were better in treatment group than those in control group(P<0.05). The treatment group had less severe subjective dry eye symptoms, longer BUT, fewer FL, and more SⅠt.

CONCLUSION:Combined use of carboxymethylcellulose sodium eye drops and rhEGF can relieve the dry eye symptoms and maintain the tear film stable after phacoemulsification effectively. Therapeutic effects of combined utilization are better than that of carboxymethylcellulose sodium eye drops used alone.