AIM: To analyze the clinical effect of adjuvant therapy with glucocorticoid in surgical treatment of uveitis complicated cataract. In order to provide reference for clinical diagnosis and treatment.

METHODS: Clinical data of patients with uveitis complicated cataract who received treatment at our hospital from 2013 to 2015 were analyzed. Patients were divided into two groups by different therapies, Group A: intraoperative injection with triamcinolone, Group B: without treatment of triamcinolone. The near and future curative effect in the two groups patients were compared.

RESULTS: A total of 68 patients were analyzed, Group A had 35 cases(37 eyes), Group B had 33 cases(34 eyes). Group A patients had a higher rate of patients with a corrected visual acuity more than 0.5 than that of Group B patients(χ²=4.094, P=0.043). There was no significant difference in intraocular pressure between the two groups(P>0.05). Anterior chamber inflammation of the observation group patients were lower than the control group, the difference was statistically significant(χ²=15.900, P=0.001).Seven days after surgery, Group A patients had a higher levels of SOD in aqueous humour and lower levels of MDA and TNF-α in aqueous humour than these of Group B patients(P>0.05). Group A patients had a lower 1 year recurrence rate than that of Group B patients(14%,5/35 vs 33%,11/33; Log-rank χ²=4.004, P=0.045).

CONCLUSION: Intraoperative anterior chamber injection with triamcinolone can significantly improve the curative effect in surgical treatment of uveitis complicated cataract.