AIM: To observe the clinical effect of 532nm laser combined with a traditional Chinese patent called He xue ming mu tablets in the treatment of diabetic retinopathy in patients with severe non proliferative diabetic retinopathy.

METHODS: A total of 120 patients(226 eyes)diagnosed by the clinic for severe non-proliferative diabetic retinopathy diabetic retinopathy patients were randomly divided into treatment group and control group. The patients underwent combined therapy defined as treatment group(Group A), the treatment process and took He xue ming mu tablets orally for 1-3mo defines a separate line. The patients with laser photocoagulation treatment as the control group(Group B). After 1, 2 and 3mo after treatment, the retinal hemorrhage and visual function of the patients in the two groups were observed, and the fundus fluorescein angiography in 3mo after treatment was observed.

RESULTS: Two groups of patients in the different treatment measures were taken after 1-2mo, patients suffering from eye visual function recovery was significantly better than the control group(P<0.05). But up to 2mo after the treatment, the treatment group and the control group eyes visual function index was no significant difference. Compared with the control group, the patients in the treatment group had significant advantages in terms of retinal hemorrhage, exudation, edema and fundus(P<0.05).

CONCLUSION: The severe non-proliferative diabetic retinopathy diabetic retinopathy treated by laser combined with He xue ming mu tablets treatment, can effectively shorten the eyes with visual function recovery speed, and can promote the absorption of retinal hemorrhage and exudation rate, reduce the secondary damage to the laser has a certain role.