AIM: To observe the effects of intravitreous injection of anti-VEGF drug and PRP combined with filtering surgery for neovascular glaucoma.

METHODS:Twenty-three eyes of 21 patients with neovascular glaucoma were enrolled. The patients of ocular media transparency were treated with intravitreous injection of anti-VEGF drug and PRP combined with filtering surgery. The patients of ocular media opacity were treated with vitrectomy or cataract surgery in the meantime. All cases were followed for 3mo, IOP control were observed after treatment.

RESULTS:One patient visual acuity improved significantly, all remaining stable or slightly improve visual acuity. All case showed regress at different degree of the iris neovessels. There was significant difference between before and after treatment(P=0.00).

CONCLUSION:The intravitreous injection of anti-VEGF drug and PRP combined with filtering surgery for neovascular glaucoma provide more rapid control of IOP. It is a better choice of neovascular glaucoma.