玻璃体内注射酮咯酸治疗白内障术后慢性黄斑囊样水肿
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Clinical research of intravitreal ketorolac for the treatment of chronic cystoid macular edema after cataract surgery
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    摘要:

    目的:探讨玻璃体内注射酮咯酸治疗白内障术后慢性黄斑囊样水肿的临床疗效。

    方法:选取2014-03/2016-02我院收治的白内障手术后并发黄斑囊样水肿患者38例,行玻璃体内注射酮咯酸治疗。治疗后,采用荧光素血管造影术(FFA)和光学相干断层扫描(OCT)进行临床检查,观察临床疗效,对比分析治疗前及治疗后2、4wk,3、6mo患者的矫正视力变化、眼压、黄斑区中心视网膜厚度。

    结果:与治疗前相比,玻璃体内注射酮咯酸治疗后FFA显示患者渗漏显著地减低,患者黄斑区水肿消退,同时,矫正视力显著提高,差异有统计学意义(P<0.05),眼压显著改善,差异有统计学意义(P<0.05),黄斑区平均厚度显著减少,差异有统计学意义(P<0.05)。

    结论:玻璃体内注射酮咯酸治疗白内障术后慢性黄斑囊样水肿有良好的治疗效果。

    Abstract:

    AIM:To investigate clinical efficacy of intravitreal ketorolac for the treatment of chronic cystoid macular edema after cataract surgery.

    METHODS:A total of 38 patients with postoperative cystoid macular edema after cataract surgery coming to our hospital for treatment at 2014-2016 were collected. And the patients were treated with intravitreal ketorolac. After treatment, the patients were clinical examined with using optical coherence tomography(OCT)and fundus fluorescein angiography(FFA). And the clinical efficacy was observed. The corrected visual acuity, intraocular pressure and central retinal thickness of the cystoid macular area after cataract surgery were compared and analyzed before and after treatment in different periods(2 and 4wk, 3 and 6mo).

    RESULTS:Comparing with before treatment, the leakage was significantly reduced at the FFA after intravitreal ketorolac for the treatment of chronic cystoid macular edema. And the cystoid macular edema in patients regressed. At the same time, the corrected visual acuity was significantly increased(P<0.05), and the intraocular pressure was significantly improved(P<0.05), and the average macular thickness was significantly reduced(P<0.05). The difference was statistically significant.

    CONCLUSION:Intravitreal ketorolac for the treatment of chronic cystoid macular edema after cataract surgery has a good clinical efficacy. There is a important clinical significance.

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马君择.玻璃体内注射酮咯酸治疗白内障术后慢性黄斑囊样水肿.国际眼科杂志, 2016,16(12):2332-2334.

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  • 收稿日期:2016-07-26
  • 最后修改日期:2016-11-08
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  • 在线发布日期: 2016-11-23
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