AIM: To assess the impact of binocular diplopia on vision-related quality of life in adult patients with ocular motility disorders.

METHODS: Retrospective case-series study. A total of 112 binocular diplopic patients with ocular motility disorders who received treatment in the First Affiliated Hospital of Huzhou University and 40 normal subjects were included in this study from Oct.2013 to Mar.2016. Vision-related quality of life was evaluated by the Chinese version of the 25-item National Eye Institute Visual Functioning Questionnaire(CHI-NEI-VFQ-25).

RESULTS: Statistically significant differences between binocular diplopic patients with ocular motility disorders and normal group were found in general health status, overall vision, near activities, distant activities, social functional, mental health, social role difficulties, independency, driving, and perimetry, except for the degree of eye pain(P=0.31)and color vision(P=0.34).

CONCLUSION: This study suggests that binocular diplopic status maybe an important factor affecting vision-related quality of life seriously for patients with ocular motility disorders. Physicians treating binocular diplopic patients with ocular motility disorders should recognize these quality of life issues and address them accordingly.