方法：选取2015-01/2016-02在我院行白内障超声乳化术联合人工晶状体植入术的白内障患者93例112眼，随机分为微切口组(47例52眼)和传统切口组(46例60眼)，微切口组行2.2mm同轴微切口，传统切口组行3.2mm切口，观察两组平均超声乳化能量(AVE)、有效超声乳化时间(EPT)、角膜内皮细胞计数等。

结果：微切口组和传统切口组术前及术后角膜内皮细胞比较差异无统计学意义(P>0.05)； 术后3mo微切口组和传统切口组角膜内皮细胞丢失率分别为(12.09±4.14)%和(13.24±5.44)%，差异比较无统计学意义(P>0.05)； 微切口组AVE为(10.01±3.21)%，明显低于传统切口组，差异比较有统计学意义(P<0.05)； 两组EPT比较差异无统计学意义(P>0.05)； 微切口组和传统切口组术前及术后裸眼视力(LogMAR)比较差异无统计学意义(P>0.05)； 微切口组术后1wk、1、3mo散光度为0.47±0.12、0.40±0.10、0.36±0.12D，明显小于传统切口组，差异比较有统计学意义(P<0.05)； 两组术中及术后未发现有严重并发症。

结论：2.2mm微切口超声乳化手术可有效节省超声能量，减少手术源性散光，有利于提高术后视觉质量，对角膜内皮细胞的损伤与传统切口无明显差异。

METHODS: From January 2015 to February 2016, 93 cases with 112 eyes who underwent cataract phacoemulsification combined with intraocular lens implantation in our hospital, were selected and randomly divided into micro incision group(47 cases 52 eyes)and traditional incision group(46 cases 60 eyes),micro incision group underwent 2.2mm coaxial micro incision, traditional incision group underwent 3.2mm incision. We observed average phacoemulsification energy(AVE), effective phacoemulsification time(EPT), corneal endothelial cell count of the two groups.

RESULTS: Preoperative and postoperative corneal endothelial cells of two groups showed no significant difference(P>0.05). The loss rate of corneal endothelial cells in the micro incision group and the traditional incision group were(12.09±4.14)% and(13.24±5.44)%, and the difference was not statistically significant(P>0.05). Micro incision group AVE was(10.01±3.21)%, significantly lower than that of the traditional incision group(P<0.05). There was no significant difference in EPT between the two groups(P>0.05). There was no significant difference on the preoperative and postoperative naked eye LogMAR vision between the micro incision group and the traditional incision group(P>0.05). The micro incision group postoperative 1wk, 1 and 3mo astigmatism were 0.47±0.12, 0.40±0.10 and 0.36±0.12, which was significantly less than that of the traditional incision group(P<0.05). No serious complications were found in the two groups intraoperatively and postoperatively.

CONCLUSION: The new surgery 2.2mm micro incision phacoemulsification can effectively save ultrasonic energy, reduce surgical astigmatism, and is conducive to improve the visual quality. Its damage to corneal endothelial cells is similar to traditional incisions.