AIM:To review the efficacy of SMILE and femtosecond laser-guided LASIK(FS-LASIK)in correction of myopia.

METHODS:The PubMed, Cochrane Library, SciVerse, WanFang Data and CNKI databases were searched for Meta-analysis of literature comparing FS-LASIK and SMILE outcomes.

RESULTS:A total of 5 literatures met the inclusion criteria of this study, a total of 689 cases(999 eyes). Meta-analysis showed: SMILE and FS-LASEK myopia treatment effectiveness \〖OR=0.83, 95%CI=(0.52, 1.33)\〗, predictability \〖OR=0.54, 95%CI=(0.22, 1.29)\〗 and security \〖OR=1.10, 95%CI(0.80, 1.51)\〗 no statistically significant difference.

CONCLUSION:SMILE and FS-LASIK correction of myopia is safe, effective, have good vision correction effect. However, due to the low quality of the included studies and the instability of the statistical results, the above conclusions need to be further validated by more rigorous randomized controlled trials.