AIM:To guide clinical prevention for the occurrence of diabetic retinopayhy(DR)by researching the correlation between renal function and the occurrence of retinopathy in patients with type 2 diabetes mellitus.

METHODS:In this study, 295 cases were included. According to the fundus situation we divided all the cases into DR group and non-DR group. The relevant indicators of the renal function of patients in the two groups was comparatively analyzed.

RESULTS:Compared with those of non-DR group, 24h urinary protein(24h-UPr), urinary albumin / creatinine ratio(ACR), serum creatinine(Scr), blood urea nitrogen(BUN)and serum uric acid(UA)of DR group were significant higher. The creatinine clearance rate(CCR), glomerular filtration rate(eGFR)in non-DR group had no difference with those of DR group.

CONCLUSION:There has a correlation between 24h-UPr, ACR, Scr, BUN, UA and DR patients with DM, while the CCR and eGFR were not correlated with the occurrence of DR in patients with DM.