AIM: To observe the interocular symmetry of retinal ganglion cell complex(GCC)parameters by spectral-domain optical coherence tomography in healthy middle-young age population.

METHODS: A cross-sectional observational study. Fifty-three subjects and 106 eyes were enrolled to compare the bilateral axial length(AL), full retina thickness(FRT), outer retina thickness(ORT), mean macular GCC thickness, focal loss volume(FLV)and global loss volume(GLV). And to evaluate the correlation between the interocular differences of GCC, FLV and GLV(△GCC, △FLV and △GLV)to age, gender, the interocular differences of AL and FRT(△AL and △FRT).

RESULTS: There were no significant interocular difference revealed by pared-samples t tests in all the parameters(P>0.05)except AL(t=2.241, P=0.029).△FRT had positive correlation to △GCC(r=0.321, P=0.019)while negative correlation to △GLV(r=-0.356, P=0.009).

CONCLUSION: Interocular symmetry of GCC parameters was observed in healthy middle-young age subjects, which did not change with the variation of age, gender and interocular differences of AL.