AIM: To investigate the correlation among the difference in the diopter, axial length and the choroidal thickness interocular difference in anisometropia

METHODS: A retrospective serial cases analysis was performed. Sixty-six anisometropia patients who accepted measurement of choroidal thickness and axial length were recruited in First People's Hospital of Xiantao from Sep.2015 to May 2016. The subjects were divided into three groups according to the difference of diopter. Group 1: the difference of diopter <1.00D, 13 males and 9 females, aged 7-14 years old. Group 2: the difference of diopter >1.00D and <2.50D, 12 males and 10 females, aged 7-16 years old. Group 3: the difference of diopter >2.50D and <5.0D, 12 males and 10 females, aged 7-18 years old.

RESULTS: The difference of diopter and subfoveal choroidal thickness(SFCT)showed statistically significant difference between 3 groups. In group 1, the difference of diopter showed no significant correlation with the difference of axial length and SFCT(r=0.192, P=0.396; r=0.182, P=0.418). In group 2, the difference of diopter showed positive correlation with the difference of axial length(r=0.582, P<0.01), and SFCT(r=0.658, P<0.01). In group 3, the difference of diopter showed positive correlation with the difference of axial length(r=0.912, P<0.01), and SFCT(r=0.967, P<0.01).

CONCLUSION: The diopter, axial length and SFCT of two eyes show statistically significant difference in different extent anisometropia. The greater the extent of anisometropia, the stronger the correction of SFCT and diopter.