AIM: To observe the effect of amniotic membrane transplantation(AMT)in exposure keratitis.

METHODS: A prospective study of 14 cases(19 eyes)with exposure keratitis were treated with AMT in our hospital from September 2015 to September 2016. The patients were resistant to various conventional medications. The time of amniotic membrane absorbed, corneal opacification, fluorescein staining, visual acuity, complications and recrudescence were observed after transplantation.

RESULTS: Amniotic membrane started to dissolve in 3-5d and fell off within 7-14d after transplantation in all patients. Slit-lamp examinations showed that the cornea turned transparent in 16 eyes. There were significant diffrrences in the scores of corneal opacification and fluorescein staining at 28d after treatment compared before treated(P<0.05). Visual acuity increased in all patients to varying degree with no complications.

CONCLUSION: AMT has a good effect in the treatment of exposure keratitis.