AIM: To explore the effect of hypertonic sugar eyes drops with local to the oxygen therapy for severe corneal edema after cataract surgery.

METHODS: Totally 68 patients(68 eyes)with severe corneal edema after phacoemulsification were selected from January 2014 to December 2015 in our hospital, who were aged 53-80(64.45±4.24), including 30 males and 38 females. According to different treatment, they were divided into treatment group(34 cases)given conventional therapy + hypertonic sugar eyes drops with local to the oxygen therapy, the control group(34 cases)given conventional treatment + hypertonic sugar eyes drops. Visual acuity and corneal situation were observed during the treatment.

RESULTS: Corneal edema fade time of treatment group was 11.62+0.53d, that of control group was 15.23±0.62d, the difference between the two groups was significant(P<0.05). Preoperative best corrected visual acuity(BCVA)and corneal endothelial cell count had no significantly difference between the two groups while the corneal endothelial cell count were significantly different compared with postoperative of the two groups(P<0.05). At 7d after treatment, the BCVA and corneal endothelial cell count had significantly difference between the two groups(P<0.05), which did not have significant difference at 1mo after treatment(P>0.05). The effective rates of the two groups was significantly different(P<0.05).

CONCLUSION: Hypertonic sugar eyes drops with local to the oxygen therapy is effective for severe corneal edema after cataract surgery.