颅内动脉瘤患者的视网膜改变
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2015年三星眼科医院基金


Retina findings in intracranial aneurysm patients
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Supported by 2015 Samsung Eye Hospital Grant.

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    摘要:

    目的:评价患有颅内动脉瘤(intracranial aneurysm, ICA)的眼底表现,以明确ICA和可辨别的视网膜改变的关系。

    方法:共分析了46位已经在神经外科诊断颅内动脉瘤患者的病历和眼部检查图像。所有的患者接受了包括荧光血管造影(fluorescein angiography, FAG)在内的眼科检查。此外,玻璃膜疣、黄斑变性、棉绒斑、硬性渗出、视网膜出血、动脉变细、动-静脉交叉征、臂-视网膜循环时间、动-静脉循环时间都进行了分析。ICA患者(组1)的检查结果和22例特发性视网膜前膜患者未患病眼(组2)的结果进行了比较。

    结果:两组患者的平均年龄分别为60.02岁(组1)和60.68岁(组2)(P=0.70)。高血压的患病率在两组中相似。两组中均未发现患视网膜大动脉瘤的患者。两组之间玻璃膜疣、黄斑变性、棉绒斑、硬性渗出、视网膜出血、动脉变细和动-静脉交叉征的情况无显著差异。平均臂-视网膜循环时间也未发现显著差异。

    结论:我们未发现有任何证据证明ICA患者FAG检查和眼底有特殊改变。

    Abstract:

    AIM: To evaluate fundus findings in patients with intracranial aneurysm(ICA)to determine the relation between ICA and distinguishable retinal features.

    METHODS: We analyzed the medical records and ocular images of 46 patients with previously diagnosed ICA referred from the Neurosurgical Department. All patients underwent ophthalmologic evaluation including fluorescein angiography(FAG). Furthermore, the presence of drusen, macular degeneration, cotton wool spot, hard exudates, retinal hemorrhage, arteriolar attenuation, A-V crossing signs, arm-to-retina time, and A-V transit time were evaluated. The results of ICA patients(Group 1)were compared with those of 22 idiopathic epiretinal membrane patients with unaffected eyes(Group 2).

    RESULTS: Mean ages were 60.02y(Group 1)and 60.68y(Group 2)respectively(P=0.70). The prevalence of hypertension was similar in both groups. No case with retinal macroaneurysm was found in either group. The presence of drusen, macular degeneration, cotton wool spot, hard exudates, retinal hemorrhage, arteriolar attenuation, and A-V crossing sign was not significantly different between the two groups. Mean arm-to-retina time was not significantly different in two groups, either.

    CONCLUSION: We cannot find any evidence that the patients with ICA shows specific changes in the FAG and fundus.

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Sung Il Kang, Kyung Tae Kang, El Kim,等.颅内动脉瘤患者的视网膜改变.国际眼科杂志, 2017,17(7):1209-1211.

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  • 收稿日期:2016-02-26
  • 最后修改日期:2017-04-07
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  • 在线发布日期: 2017-06-26
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