AIM: To explored the treatment effects of retinal laser photocoagulation and the applications of color Doppler flow imaging(CDFI)in the diabetic retinopathy.

METHODS: We collected 60 patients(120 eyes)with diabetic retinopathy(Ⅲ～Ⅳstage)from February 2013 to February 2014 in Anyang Eye Hospital admitted in fundus disease department. The health control(HC)group of 55 normal people was established simultaneously. Ocular blood flow velocity of the 55 normal people(110 eyes)and the 60 patients(120 eyes)was examined by CDFI of central retinal artery(CRA)and posterior ciliary artery(PCAs)using the PHILIPS HD6. Peak systolic velocity(PSV)was recorded. The examinations of CDFI, electroretinogram(ERG)and the vision were performed in pre-operation, 1,7d, 1, 3 and 6mo postoperatively.

RESULTS: Compared the PSV of CRA of the DR group before and after photocoagulation to the data of the HC group, there was a significant difference(P<0.05); compared the PSV of CRA of the DR group after photocoagulation with the data before, there was a significant difference(P<0.05). Compared the PSV of PCAs of the DR group before and after photocoagulation to the data of the HC group, there was a significant difference(P<0.05); compared the PSV of PCAs of the DR group after photocoagulation with the data before, there was a significant difference at 1d postoperatively(P<0.05), there was no significant difference at 7d, 1, 3 and 6mo(P>0.05). Compared the aA and bA of ERG of the DR group before and after photocoagulation to the data of the HC group, there was a significant difference(P<0.05). Compared the aA and bA of ERG of the DR group after photocoagulation with the data before, there was a significant difference(P<0.05). Compared the aT and bT of ERG of the DR group before and after photocoagulation to the data of the HC group, there was a significant difference(P<0.05); compared the aT and bT of ERG of the group DR after photocoagulation with the data before, there was no significant difference(P>0.05). The vision of 49 cases(98 eyes)was improved 1 to 3 rows, the effective rate was 82%.The vision of 11 cases(22 eyes)remained constant.

CONCLUSION: Retinal laser photocoagulation is an effective treatment to diabetic retinopathy patients, which can significantly reduce the peak systolic velocity of the central retinal artery, improve and stabilize the condition, protect visual function in long-term clinical effect. Color doppler flow imaging can observe the changes of ocular vessel flow velocity in diabetic' eyes noninvasively, repeatedly and in real time, providing a basis for clinical treatments.