AIM:To compare the clinical effects of 25G+ and 27G+ transconjunctival sutureless vitrectomy in treating idiopathic macular hole.

METHODS: We retrospectively reviewed the clinical outcomes of 56 eyes(56 patients)with idiopathic macular hole which were treated with micro-incision vitrectomy from June 2015 to September 2016. Patients were divided into two groups, 28 patients(28 eyes)were treated with 25G+ vitrectomy and the rest(28 eyes)were treated with 27G+ vitrectomy. The operative time and intraoperative complications were recorded and patients were followed up for 3-6mo. During the follow up period, best correct vision acuity(BCVA), intraocular pressure, macular hole healing and postoperative complications were documented and statistically analyzed.

RESULTS: BCVA in two groups were significantly improved after surgery(P<0.001)and there was no significant difference between the two groups(P=0.84). No serious complications occurred. No statistically significant difference was found between the two groups in surgical time and healing rate of macular hole(P=0.57, 0.64). The incidence of low intraocular pressure(IOP<10mmHg)in 27G+ group was lower than that in 25G+ group on the first day after surgery(P=0.31). There was no significant difference between preoperative and postoperative intraocular pressure at 1wk after operation in both groups(P=0.72, 0.92).

CONCLUSION: Both 25G+ and 27G+ vitrectomy are safe and effective technique in treating idiopathic macular hole. Besides, 27G+ showed better superiority on the maintenance of intraocular pressure and reduce the trauma.