AIM: To observe the clinical effect of combined cataract and primary open-angle glaucoma underwent phacoemulsification and glaucoma drainage device implantation.

METHODS: We selected in our hospital from January 2014 to February 2016, 42 cases(42 eyes)with primary open-angle glaucoma with cataract. According to random number table method, all of the patients were randomly divided into two groups, control group and study group. In control group, 21 patients(21 eyes)underwent trabecular resection combined phacoemulsification; in study group patients, 21 patients(21 eyes), underwent EX-PRESS glaucoma drainage device combined phacoemulsification. Compared parameters included postoperative complications and filtering bleb, visual acuity, intraocular pressure(IOP)and other clinical indicators between two groups.

RESULTS: Preoperative IOP of two groups was no significantly different(P>0.05). Postoperative IOP at each time point was significantly lower than before treatment(P<0.05). At 1d, 1 and 4wk after treatment, IOP of the study group was significantly lower than the control group(all P<0.05); at 12wk after treatment, IOP of the two groups was not significantly different(P>0.05). At 12wk after treatment, surgical success rate of study group was 95%, significantly higher than that of control group 71%(P<0.05). The postoperative best corrected visual acuity of two groups was no significantly different(P>0.05). At 12wk after treatment, 21 patients in study group were shown as functional filtering bleb, while in the control group 18 cases was functional filtering bleb.

CONCLUSION:Using EX-PRESS glaucoma drainage device combined with phacoemulsification in treating cataract with primary open-angle glaucoma is reliable, the curative effect is better than that by trabeculectomy combined with phacoemulsification treatment.