AIM: To evaluate the effect of bupivacaine in non-catheter infiltration anesthesia during vitretomy operation.

METHODS: Fifty-eight patients(58 eyes)with vitreous retinal surgery were selected. Patients were randomly divided into observation group(28 eyes)and control group(30 eyes). The observation group were received non-catheter infiltration anesthesia. The control group were received traditional Sub-Tenon's block(STB). Degree of pain, basic vital signs, the duration of anesthesia and analgesia grade were recorded and compared between two groups.

RESULTS: No significant difference was found in the 11-point numeric rating scale(NRS-11 scoring)of anesthesia process, sclera incision, intraocular operation and the end of operation between two groups(P>0.05). The difference were not significant in heart rate and blood pressure between two groups(P>0.05). There was statistically significant difference in the duration of anesthesia between two groups(P<0.05).

CONCLUSION: Both groups can provide the same anesthetic effect. Compared to STB, non-catheter infiltration anesthesia takes short time, and it is a safe and effective anesthesia methods. In addition, compare to the mixture of bupivacaine and lidocaine injection, bupivacaine injection can provide the same anesthetic effect.