AIM: To analyze the biometric parameters before and after cataract surgeries of the cataract eyes with high myopia, and to provide reference for the calculation of intraocular lens diopter for cataract eyes with high myopia.

METHODS: Totally 152 cataract eyes with high myopia were selected. All the axial lengths were equal to or more than 26mm. The preoperative axial length, corneal curvature, anterior chamber depth, and lens thickness were measured before cataract surgery, and also the corneal curvature and anterior chamber depth were measured 3mo after cataract surgery. The relationships between the parameters were analyzed, and the postoperative anterior chamber depth was analyzed by multiple linear regression analysis.

RESULTS: The correlation between the preoperative axial length and preoperative corneal curvature, lens thickness was positive separately(r=0.236, r=0.216; P<0.05). There was no correlation between preoperative axial length and preoperative anterior chamber depth(P>0.05). And there was no correlation between preoperative anterior chamber depth and preoperative corneal curvature(P>0.05). There was negative correlation between preoperative anterior chamber depth and preoperative lens thickness(r=-0.513, P<0.05). And there was positive correlation between postoperative anterior chamber depth and preoperative axial length, preoperative anterior chamber depth, preoperative corneal curvature and postoperative corneal curvature separately(r=0.374, r=0.364, r=0.333, r=0.356; P<0.05). There was no correlation between postoperative anterior chamber depth and preoperative lens thickness(P>0.05). The multiple linear regression equation was: postoperative anterior chamber depth = -2.592 + 0.091 × preoperative axial length +0.078 × preoperative corneal curvature +0.491 × preoperative anterior chamber depth.

CONCLUSION: By measuring the preoperative axial length, corneal curvature and anterior chamber depth, the postoperative anterior chamber depth can be calculated by using the postoperative anterior chamber depth multiple regression equation, so as to provide a reference for the calculation formula of intraocular lens diopter of cataract patients with high myopia.