AIM: To evaluate the efficacy of implantable collamer lens(ICL)-V4c implantation in the correction for high myopia.

METHODS: This retrospective analysis collected twenty-five patients(43 eyes)with high myopia treated with ICL/TICL implantation from September to December 2016 at Department of Ophthalmology, West China Hospital. Routine ophthalmic examinations were performed. The patients were followed 3mo to monitor uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), refractive error, intraocular pressure, corneal endothelial cell count, contrast sensitivity and scores for Quality of Life Impact of Refractive Correction Questionnaire(QIRC). Statistical analyses were performed using repeated measures ANOVA, LSD-t test and paired-samples T test.

RESULTS: Postoperative UCVA and BCVA were significantly higher than before surgery(all P<0.01). Postoperative spherical mirrors at all time points were lower than before surgery(all P<0.01), and there was no significant difference between the different time point postoperative(all P>0.05). The safety index in 3mo postoperatively was 1.38±0.24 and the effective index was 1.22±0.15. There was no statistical difference in intraocular pressure between preoperative and postoperative time points(F=1.464, P=0.215). There was no statistical difference in endothelial cell density at 3mo after surgery compared to preoperative(t=-0.544, P=0.586). The postoperative Log contrast sensitivity(LogCS)of 12.0 cycles per degree(c/d)and 18.0 c/d were significantly higher compared to the preoperative(F=4.347, P=0.010; F=4.539, P=0.005; respectively), but other(the postoperative LogCS of 3.0 c/d and 6.0 c/d)differences were statistically insignificant(F=1.094, P=0.354; F=1.325, P=0.271; respectively). There was no significant difference in the amount of change in the QIRC scores between preoperative and postoperative(F=2.669, P=0.094).

CONCLUSION: ICL V4c implantation is a safe and effective method for the correction of high myopia.