AIM: To discuss the clinical effects of laser iridoplasty combined with YAG laser or traditional trabeculectomy in the treatment of glaucoma.

METHODS: The clinical data of 60 cases(60 eyes)of patients with glaucoma were retrospectively analyzed. The patients who underwent laser iridoplasty combined with YAG laser iridotomy were included in observation group(n=38, 38 eyes), and those who underwent traditional trabeculectomy were included in control group(n=22, 22 eyes). The changes of intraocular pressure(IOP), angle opening distance(AOD500), central anterior chamber depth(ACD), corneal endothelial cell density(ECD)were compared between the two groups before operation and at 1mo, 3mo and 12mo after operation, and the occurrence of complications within 12mo after operation were analyzed in the two groups.

RESULTS: At 1mo, 3mo and 12mo after operation, the IOP level in the two groups was decreased significantly compared with that before operation, and the level in observation group was significantly lower than that in control group(P<0.05). The levels of AOD500 and ACD in observation group were significantly higher than those before treatment and than those in control group(P<0.05). There was no statistically significant difference in the ECD level of observation group compared with that before operation(P>0.05), but the level was significantly higher than that in control group(P<0.05). Within 12mo after operation, the total incidence rate of complications in observation group was significantly lower than that in control group(P<0.05).

CONCLUSION: Laser iridoplasty combined with YAG laser for glaucoma can obtain an ideal treatment effect, and its safety is better than traditional trabeculectomy and it is beneficial to the recovery of ocular function.