AIM: To observe the clinical efficacy and safety of regional refractive multifocal intraocular lens SBL-3.

METHODS: Eighty-five senile cataract patients(130 eyes)who underwent phacoemulsification and intraocular lens implantation in our hospital were divided into two groups according to the difference of implanted intraocular lens: patients with regional refractive multifocal intraocular lens(MIOL)42 example(65 eyes)as an observation group, 43 patients(65 eyes)of a single-focus aspheric intraocular lens were used as a control group. Three months after operation, the indicators were: uncorrected distance visual acuity(UCDVA), uncorrected intermediate visual acuity(UCIVA), uncorrected near visual acuity(UCNVA), and spherical equivalent power(SE). The naked eye defocus curve was measured and the patient's subjective visual quality was investigated by questionnaire, including the rate glasses removal, visual interference symptoms and satisfaction.

RESULTS: At 3mo after operation, UCDVA was significantly improved in both groups compared with preoperative, and the difference was statistically significant(P<0.01). However, there was no significant difference between the two groups(P>0.05), while UCIVA and UCNVA in the observation group were significantly better than the control group, the difference was statistically significant(P<0.01). At 3mo after operation, the difference of computerized optometry spherical equivalent power(SE)of the two groups was statistically significant(P<0.01). At 3mo after operation, the naked eye defocus curve of the observation group was stable in the range of +0.50 to -3.00D, the LogMAR visual acuity was below 0.301, and the curve began to rise slowly after -3.50D; the control group showed trough between ±0.5D, both ends are rising rapidly. At 3mo postoperatively, the proportion of patients with visual interference symptoms in the observation group(4/42)was not significantly different from that in the control group(2/43)(P=0.433). The glasses removal rate of the observation group was 97.6%(41/42), control group was 18.6%(8/43), the difference was statistically significant(χ²=4.318, P=0.038). In the observation group, the single eye distance satisfaction was 92.3%, and the control group was 93.8%. The difference was not statistically significant(P=1.000). The observation group had a single eye near fullness of 98.5%(64/65)and the control group was 16.9%(11/65), the difference was statistically significant(χ²=88.526, P<0.01).

CONCLUSION: The regional refraction MIOL can provide good near-intermediate-distance and full-distance uncorrected visual acuity. It can meet the needs of the patients at daily, distance-middle distance-near use. Postoperative visual interference symptoms were fewer and patient satisfaction was higher.