AIM: To study the effect of orthokeratology lens on myopia patients and their corneal morphology and diopter.

METHODS: Totally 150 cases of myopia children admitted to our hospital from January 2016 to January 2017 were selected and divided into the orthokeratology lens group and the spectacles group according to the wishes of the patients and their families. Visual acuity of all patients was examined before and 1a after treatment. corneal curvature, corneal thickness and diopter were recorded and the complications during treatment was observed as well.

RESULTS: The uncorrected visual acuity of orthokeratology lens group was significantly better than that of spectacles group(P<0.05). The corneal curvature of orthokeratology lens group was significantly lower than that of spectacles group(P<0.05). There was no significant difference in central corneal thickness of the two groups before and after treatment(P>0.05). There was no significant difference in diopter between the two groups before treatment(P>0.05); the diopter of orthokeratology lens group was significantly lower than that of spectacles group(P<0.05). The incidence of complications in orthokeratology lens group was 14.3%, which was significantly higher than that in spectacles group 4.9%(P<0.05).

CONCLUSION: The treatment of myopia with orthokeratology lens has a significant effect, but there are many complications in the patients. Therefore, in the clinical application process, specific precautions should be taken against the factors that may cause complications, so as to make the treatment process safer.