AIM: To observe the change of axial length in anisometropia myopia with simple eye receiving orthokeratology treated.

METHODS: Totally 56 cases(112 eyes)with anisometropia myopia receiving monocular orthokeratology treated were divided into two groups. For every case, eye wearing orthokeratology was assigned to the experimental group and another eye to the control group. The refraction, corneal curvature and axial length were measured at pre-wear and 1mo discontinuation after wearing orthokeratology 1y.

RESULTS: The statistically significant changes(t=2.8631, P<0.001)of increase in refraction were(0.29±0.15D),(0.76±0.41D)for the experimental and control group respectively. The horizontal corneal curvature was(0.27±0.11D)and(0.20±0.14D)for two groups, and there was no statistically significant difference(t=0.8204, P>0.05). The increase of axial length was(0.14±0.10)mm and(0.32±0.14)mm for the experimental and control group, respectively, and the increase was statistically significant(t=2.7518,P<0.001).

CONCLUSION: Orthokeratology can slow down myopia progression by reducing axial length to control myopia increase.