目的：观察翼状胬肉切除联合角膜缘干细胞移植术后应用角膜绷带镜对眼表修复的影响。

方法：选取2016-01/2018-01在我院眼科就诊的单眼初发翼状胬肉患者52例，行翼状胬肉切除联合角膜缘干细胞移植术加戴绷带镜者26例为试验组，术后不加戴绷带镜者26例为对照组，分别于手术前后观察两组患者眼表疾病指数(OSDI)问卷评分、泪膜破裂时间(BUT)、角膜荧光素染色(CFS)评分。

结果：与对照组相比，术后2wk，1mo试验组患者BUT延长，OSDI、CFS分值降低(均P<0.05)。与术前相比，术后2wk两组患者BUT均缩短，OSDI、CFS分值均增高(P<0.05)； 术后1mo试验组患者BUT、OSDI和CFS分值与术前均无差异(P>0.05)，而对照组患者BUT较术前仍缩短，OSDI、CFS分值仍增高(均P<0.05)。

结论：翼状胬肉切除联合自体角膜缘干细胞移植后加戴角膜绷带镜在术后早期是一种促进角膜愈合、提高泪膜稳定性、减少术后不适的安全方法，利于眼表修复，具有一定的临床应用价值。

METHODS: Totally 52 patients with unilateral primary pterygium were selected from January 2016 to January 2018 in the ophthalmology department of our hospital. All 26 cases(26 eyes)underwent pterygium excision combined with limbal stem cell transplantation and who were placed with bandage lens as the experimental group, the other 26 cases(26 eyes)without bandage lens placed as the control group. Ocular surface disease index(OSDI)questionnaires, tear break-up time(BUT), and corneal fluorescein staining(CFS)were recorded before operation and after operation.

RESULTS: BUT in the experimental group was longer than that in the control group(P<0.05), OSDI and CFS scores were lower than those in the control group(P<0.05)at 2wk, 1mo after operation. Compared with the preoperative situation, BUT in the two groups was shorter, OSDI and CFS scores were higher(P<0.05). At 1mo after operation there were no significant differences in BUT, OSDI and CFS between the experimental group and those before the operation(P>0.05), but in the corresponding period, BUT in the control group was still shorter, OSDI and CFS scores were still higher than those before the operation(P<0.05).

CONCLUSION: Surgical excision combined with autologous limbal stem cell transplantation and placing corneal bandage lens is a safe method to promote corneal healing, improve tear film stability and reduce postoperative discomfort in pterygium patients in the early stage after surgery, which is conducive to the repair of the ocular surface and has certain clinical application value.