AIM: To analyze the pathogens distribution and drug resistance of preschool children with infectious eye diseases in Nanyang Area.

METHODS: Totally 480 cases of preschool children(480 eyes)who were diagnosed as suspected infectious eye diseases were retrospectively analyzed. The pathogens distribution and resistance were analyzed.

RESULTS: All 144 positive cultures were cultured among 480 samples, including 122 positive bacterial cultures. Among the 122 bacterial samples, Gram-positive cocci accounted for 45.9%(56/122)with the highest proportion of Staphylococcus epidermidis of 46.4%(26/56). Gram-positive bacilli accounted for 18.9%(23/122)with the highest proportion of Corynebacterium of 82.6%(19/23). Drug susceptibility results showed that Staphylococcus epidermidis had different degrees of resistance to most antibiotics, and Klebsiella pneumoniae was completely resistant to ampicillin and piperacillin.

CONCLUSION: Gram-positive cocci are the main pathogens of preschool children with infectious eye diseases in Nanyang Area, and the resistance rate is high. It is necessary to given rational use of drugs based on drug susceptibility results.