AIM: To analyze the risk factors affecting the occurrence of vitreous hemorrhage(VH)in type 2 diabetic retinopathy(DR).

METHODS: The clinical data of 165 patients with DR admitted to the hospital from November 2016 to November 2018 were retrospectively analyzed. Multivariate Logistic regression was performed to analyze independent relevant factors of VH occurrence in patients with DR.

RESULTS: Totally 165 patients with DR, 59 cases(59 eyes)with non-proliferative diabetic retinopathy(NPDR), including 18 cases(18 eyes)with mild NPDR, 21 cases(21 eyes)with moderate NPDR and 20 cases(20 eyes)with severe NPDR. And there were 106 cases(106 eyes)with proliferative diabetic retinopathy(PDR). Among them, there were 87 cases(87 eyes)with VH, and the incidence rate was 82.1%. There were significant differences in age, systolic blood pressure, diastolic blood pressure, fasting plasma glucose(FPG), glycosylated hemoglobin(HbA1c), triglyceride(TG), cholesterol(TC), high density lipoprotein(HDL), low density lipoprotein(LDL)and creatinine(CRE)between non-VH group and VH group(P<0.05). Taking the presence or absence of VH as dependent variable, multivariate Logistic analysis showed that HbA1c was an independent risk factor for occurrence of VH(P<0.05), and HDL was an independent protective factor for occurrence of VH(P<0.05).

CONCLUSION: HbA1c and HDL are independent relevant factors influencing the occurrence of VH in patients with DR. In clinical practice, blood glucose and lipids should be strictly controlled to reduce the probability of DR progression to VH.