AIM: To analyze the efficacy and influencing factors of femtosecond laser small incision lenticule extraction(SMILE)in the treatment of different curvature myopia.

METHODS: Totally 72 patients(144 eyes)with myopia who underwent SMILE were prospectively included. According to the preoperative corneal curvature, they were divided into low curvature group(<41D, n=21 cases, 42 eyes), middle curvature group(41-46D, n=26 cases, 52 eyes)and high curvature group(>46D, n=25 cases, 50 eyes). The refraction state, uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA)and corneal optical quality were compared among the groups before operation and at 1wk after operation and at 3mo after operation, and the influencing factors of SMILE visual acuity recovery in patients with myopia were screened out.

RESULTS: There were significant differences in UCVA and BCVA at different time points before and after operation within the three groups(P<0.05), and there were no significant differences at different time points among groups(P>0.05). There were no significant differences in the spherical degree, cylindrical degree and spherical equivalent degree among the three groups at different time points(P>0.05). There was a statistically significant difference in the vector change value of subjective optometry refractive power(P<0.05), and the value in low curvature group was lower than that in middle curvature group and high curvature group(P<0.05). Multivariate Logistic regression analysis showed age, ocular axial length and preoperative spherical equivalent were related factors affecting the efficacy of SMILE surgery(P<0.05).

CONCLUSION: SMILE can better improve the visual acuity of patients with different curvature myopia, and it is safe and effective, but age, ocular axial length and preoperative spherical equivalent are related factors affecting the visual acuity after SMILE.