目的：随访观察配戴角膜塑形镜1a的不同程度近视的青少年患者，研究其在近视矫治同时对视觉质量的影响，对角膜塑形镜的安全性进行探讨。

方法：选取2016-09/2017-12就诊的-1.00～-8.00D的158例青少年近视患者，患者均配戴同一品牌的夜戴型角膜塑形镜矫治。随访观察患者配戴1a期间的视觉质量(包括像差、主观不适及视觉质量问卷调查)的改变情况。

结果：配戴角膜塑形镜后总像差RMS值均降低，总高阶像差(RMS_h)、3阶像差(RMS₃，包括彗差)及4阶像差(RMS₄，包括球差)均增加。基础近视度数越高，主观视觉不适的症状发生率越高，而戴镜前后患者的主观视觉质量总体评分无差异(P>0.05)。

结论：角膜塑形镜会造成患者客观视觉质量下降，但长期随访发现整体视觉质量对生活学习无明显影响，是一种安全有效矫治近视的手段。

METHODS: Totally 158 cases of adolescent myopia(-1.00D to -8.00D)who all wore the same brand orthokeratology lens were selected from September 2016 to December 2017. Their visual quality, including aberration detection, subjective discomfort and visual quality questionnaire was observed for 1a.

RESULTS: After wearing orthokeratology, the patients' total RMS decreased, while the RMS_h, the RMS₃(including coma)and the RMS₄(including spherical aberration)increased. The higher of baseline degree, the higher incidence of subjective visual discomfort, and the difference between pre-wearing and after was not statistically significant in subjective visual quality score(P>0.05).

CONCLUSION: The patients' objective visual quality decreased after wearing orthokeratology lens. However, the long-term observation revealed that the overall visual quality had no significant impact on lifelihood and learning, which indicates orthokeratology is a safe and effective mean of myopia curing.