AIM: To observe the changes of corneal curvature and astigmatism and anterior chamber depth after femtosecond laser-assisted LASIK for myopic astigmatism.

METHODS: One hundred and thirty-four cases(212 eyes)undergone femtosecond laser-assisted LASIK in our hospital were included. They were selected and divided into two groups based on astigmatism. The group A:astigmatism -2.00D to -5.00D, spherical equivalent -6.15±1.74D. The group B:astigmatism -0.25D to -1.00D, spherical equivalent-6.67±1.04D. Patients were examined 1wk, 1mo and 3mo. Visual acuity, intraocular pressure, refraction, corneal curvature and anterior chamber depth were recorded. The changes of corneal curvature and astigmatism and anterior chamber depth were compared. Spearman correlation analysis and independent t-test were used for statistical analysis.

RESULTS: No statistically significant difference was found in posterior corneal curvature and astigmatism and anterior chamber depth of the groups A and B at preoperative, postoperative 1wk, 1mo and 3mo(P>0.05). No statistically significant difference was found in anterior corneal curvature of the groups A and B at postoperation 1wk, 1mo and 3mo(P>0.05). One week postoperative, the anterior corneal astigmatism of the group A was statistically significant from that of 1mo and 3mo postoperative(P<0.05), there were no significant differences at 1mo, 3mo after operation(P>0.05). No statistically significant difference was found in anterior corneal astigmatism of the group Bat postoperation 1wk, 1mo and 3mo(P>0.05).

CONCLUSION: When correct high astigmatism, no significant changes of posterior corneal curvature and anterior chamber depth was found after femtosecond laser-assisted LASIK for correct myopic astigmatism. The anterior corneal curvature was stable from 1wk to 3mo.The astigmatism was stable from 1mo to 3mo.