AIM:To report the residual and treatment of subretinal perfluorocarbon liquid after vitreoretinal surgeries.

METHODS: Six cases of subretinal PFCL residual cases were surgically removed. Before and after operation, we assessed best corrected visual acuity(BCVA)and optical coherence tomography angiography(OCTA)features of retina and choriocapillaris.

RESULTS: Subretinal PFCL in the range of more than 1/5PD in diameter and 2PD in the fovea were completely removed in all cases, macular was reattached and visual acuity was improved in varying degrees. The OCTA features of two patients showed that the changes of blood flow in the superficial retina of the PFCL were small, the deep inner retinal layers blood flow disappeared, and the choriocapillaris signal were different according to the quantity of PFCL bubble.

CONCLUSION: Large PFCL bubble can be removed surgically, and small PFCL outside the macula can be observed for a long time. OCTA is helpful to observe the size and morphology of retained subretinal PFCL, and to analyze the structure and function of the retina and choroid in the lesion.