A variety of therapeutic methods can be used to treat keratoconus. This article provides practical information for clinicians to make the most appropriate choices by reviewing the treatment of keratoconus. Search for keywords such as “keratoconus” “contact lenses” “corneal collagen cross-linking” “Intacs(corneal ring)” “keratoplasty” “gene therapy” “irregular astigmatism” through a database. According to the related literature, the treatment methods of keratoconus are reviewed. Glasses and contact lenses can be used for early keratoconus, while bowman layer transplantation, penetrating keratoplasty(PK), deep anterior lamellar keratoplasty(DALK), conductive keratoplasty and gene therapy can be used in advanced disease. In addition, cross-linking can prevent keratoconus progression, and intrastromal corneal ring segments(ICRS)reduce refractive error for therapeutic purposes by flattening the deformed cornea. In general, the development of ophthalmic diagnostic techniques and treatments can slow the progression of keratoconus, thereby reducing the need for corneal transplantation in patients with advanced keratoconus. Choosing the right keratoconus treatment can help patients with vision recover and prevent blindness.