Abstract:Conjunctival reconstruction is commonly used in severe conjunctival defect caused by chemical or thermal burns. The problems of conjunctival transplantation, including shortage of autogenous conjunctiva and immunological rejection of xenogenous conjunctiva or materials, could be solved by tissue engineering conjunctiva. A scaffold material with well biocompatibility and sufficient biomechanical property plays a critical role in the construction of tissue engineering conjunctiva. In this review, the latest research progress and the existing problems of scafflod materials in tissue engineering conjunctiva were summarized.