AIM:To observe the effect of internal limiting membrane exfoliation in the treatment of PVR-C retinal detachment.

METHODS: A total of 37 cases(37 eyes)of PVR-C retinal detachment were collected from August 2015 to July 2018.All eyes were treated with 25G invasive vitrectomy combined with silicone oil filling. The internal limiting membrane was removed after indocyanine green staining,and the removal size of the inner boundary membrane to the upper and lower vascular arch. Silicone oil was taken out of the retina in 3-6mo. Followed up for 12mo after the first operation, the visual acuity, intraocular pressure, retinal reattachment and the formation of the macular membrane were observed and analyzed retrospectively.

RESULTS: The vision of all patients was improved. The intraocular pressure of 6 eyes increased within 2wk after operation, and the intraocular pressure returned to normal after treatment. All patients were followed up for 1a, macular membrane did not occur. Retinal detachment occurred again in 2 eyes due to PVR of the anterior retina. The remaining 35 eyes, silicone oil were successfully removed.

CONCLUSION: 25G micro-invasive vitrectomy combined with internal limiting membrane peeling is safe and effective in the treatment of this kind of disease, and effectively prevent the appearance of the macular anterior membrane.