Thyroid-associated ophthalmopathy(TAO)is the most common orbital disease in adults. Its ocular damage is becoming more and more serious, which causes great harm to the physical and mental health of patients. The pathogenesis of TAO is very complex and has not yet been fully elucidated. The classical theory is the theory of co-antigens. In view of the drawbacks of existing treatment schemes, it is of great significance to study the factors related to TAO and explore better treatment methods for TAO patients. In recent years, the relationship between inflammatory response and TAO has been found, therefore this article reviews the research on TAO-related inflammatory factors.