AIM: To explore the correlation between urinary microalbumin creatinine ratio and diabetic retinopathy(DR)in type 2 diabetic patients in Hefei area.

METHODS: A retrospective case analysis. 281 patients with type 2 diabetes mellitus(T2DM)hospitalized in Hefei Second People's Hospital from November 2018 to September 2019 were conducted in this study. According to the digital fundus photography, the patients were divided into diabetic retinopathy group(DR group)and non-diabetic retinopathy group(NDR group). The patients' gender, age, course of diabetes, history of hypertension, body mass index(BMI), blood urea nitrogen(BNU), urinary microalbumin creatinine ratio(UACR),fasting blood glucose, HbA1c, total bilirubin(TB), total cholesterol(TC), triglyceride(TG)were collected and risk factors of DR were analyzed.

RESULTS: A total of 281 cases, 169(60.1%)were in the NDR group and 112(39.9%)in the DR group. Logistic regression analysis and ROC curve analysis showed that the risk factors related to DR were UACR(β=0.036, OR=1.037, 95% CI: 1.019-1.056, P<0.001), the best critical value was 10.15mg/g·Cr(AUC=0.717, P<0.001); the course of diabetes(β=0.061, OR=1.063, 95% CI: 1.008-1.120, P=0.023), the best critical value was 10.5a(AUC=0.666, P<0.001).

CONCLUSION: UACR and the course of diabetes are independent risk factors for DR in some of the patients with type 2 diabetes in Hefei.