Corona virus disease 2019(COVID-19)epidemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has broken out with a vengeance, seriously threatening the global public health security. Due to the lack of specific effective drugs, effective and positive protective measures are still the most effective ways to prevent COVID-19. Clinical studies had shown that patients with COVID-19 might develop conjunctivitis symptoms. An animal experiment had also confirmed that the conjunctiva was one of the routes of SARS-CoV-2 transmission. However, current studies have gotten different or even contrary conclusions, and the relationship between SARS-CoV-2 infection and the occurrence of conjunctivitis has not been elucidated. Therefore, this article combines the latest clinical and animal studies to further elaborate the relationship between SARS-CoV-2 conjunctivatransmission and conjunctivitis, and explore the significance of conjunctiva transmission of SARS-CoV-2 protection.