AIM:To investigate the clinical effect of ultrasonic atomization of Shenmai Runmu formula on dry eyes related to meibomian gland dysfunction(MGD).

METHODS: Totally 120 cases of MGD related dry eye patients in our hospital patients were randomly divided into two groups: treatment group(ultrasonic atomization of Shenmai Runmu group)and control group(OPT intense pulse phototherapy), 60 cases each, both groups were combined with meibomian gland massage. The ocular surface comprehensive analyzer was used to detect various indicators: average non-invasive tear break-up time(NITBUTav), lower tear meniscus height(LTMH), meibomian gland score, etc. Subjective symptoms of patients' eyes were scored by questionnaire survey, and the clinical data were statistically processed.

RESULTS: There was no statistical difference between the treatment group and the control group in terms of gender, age, course of disease before treatment, and the indicators in the period from treatment start to 6mo after the treatment end(P>0.05); The total effective rate was about 94.9% in the treatment group and 96.6% in the control group(P>0.05).

CONCLUSION: Ultrasonic atomization combined with meibomian gland massage can improve the subjective symptoms and objective indexes of MGD related dry eyes. Compared with the modern medical treatment, the therapeutic effect of this method is basically the same, safe and effective, but it is more convenient and economic, which is worth popularizing in clinical application.