AIM:To explore the clinical efficacy of probing lacrimal passage combined with tobramycin eye drops in the treatment of congenital dacryocystitis.

METHODS: A total of 228 children(250 eyes)aged from 6mo-3a with congenital dacryocystitis treated in our hospital from January 2017 to June 2019 were included. They were assigned into three groups by age: 133 patients(149 eyes)aged from 6mo-1a(Group A), 62 patients(64 eyes)aged from 1-2a(Group B), and 33 patients(37 eyes)aged from 2-3a(Group C). All patients received lacrimal duct probing in surface anesthesia combined with postoperative tobramycin eye drops.

RESULTS: The probing cure rates of congenital dacryocystitis among there groups were 97.3%(Group A), 92.2%(Group B)and 83.8%(Group C), respectively. No adverse events reported. Through comparison of these three groups, the cure rate of children from 6mo-1a was the highest. The difference was statistically significant(P=0.009).

CONCLUSION: Lacrimal duct probing is effective in the treatment of congenital dacryocystitis, and it is safe and reliable to combine tobramycin eye drops(TOBREX)after surgery. The best time for treatment is 6mo-1a. The operation is simple, less complication, with high clinical value.