有晶状体眼后房型人工晶状体植入矫正近视及散光的长期临床研究
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四川省科技厅苗子工程项目(No.2018RZ0095)


Long term results of posterior chamber intraocular lens implantation for correction of myopia
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Miao Zi Project of Sichuan Science and Technology Department(No.2018RZ0095)

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    摘要:

    目的:评价有晶状体眼后房型人工晶状体植入术的长期安全性及稳定性。

    方法:回顾性非随机临床试验研究。选取2013-01/2014-12于成都爱尔眼科医院行有晶状体眼后房型人工晶状体(V4,ICL)植入手术患者64例107眼,分别于术前,术后1wk,1、3、6、12mo及术后每年随访裸眼视力(UCVA)、最佳矫正视力(BCVA)、屈光度数、眼压、拱高、角膜内皮计数、眼轴以及手术安全性、有效性等,所有患者随访至2019-12均完成术后5a或以上的末次随访。

    结果:术前BCVA(LogMAR)为-0.08(0, -0.08),术后1a裸眼视力为0(-0.076, 0),末次随访裸眼视力0.096(0, 0.221),较术后1a,末次随访裸眼视力有所下降,这种视力改变主要与眼轴较术前有明显增长有关。BCVA在术后1a及末次随访结束较术前相比均无明显改变。末次随访的手术安全指数平均为1.19±0.24,有效指数为1.00±0.29。散光晶状体在眼内长期稳定性良好,没有出现明显的旋转等。拱高的变化主要发生在术后1a内,其后变化缓慢。眼压、角膜内皮计数无明显变化。本研究中2眼分别于术后3、5a出现晶状体前囊下混浊,无青光眼、色素播散等并发症出现。

    结论:ICL植入术矫正近视具有良好的安全性、稳定性及可预测性。

    Abstract:

    AIM: To evaluate the long-term safety, efficacy and stability of posterior chamber intraocular lens(ICL)implantation for the correction of myopia.

    METHODS: This retrospective non-randomized study included 107 eyes of 64 patients who were performed ICL implantation from January 2013 to December 2014. The uncorrected visual acuity, corrected visual acuity, intraocular pressure, the lens vault, endothelial cell morphometry were collected preoperatively and followed at 1wk, 1mo, 3mo, 6mo, 12mo and every year postoperatively.

    RESULTS: The uncorrected visual acuity(LogMAR)was 0(-0.076, 0)at 1a postoperatively, and the uncorrected visual acuity 0.096(0, 0.221)decreased until last visit after the surgery. The change of visual acuity was associated with the change of axial length. The safety index was 1.19±0.24 and the efficacy index was 1.00±0.29 at the last visit postoperatively. The toric ICL implantation was stable without rotation at the last visit postoperatively. The vault of the ICL changed significantly in 1a postoperatively, but its change was smaller after 1a postoperatively. The intraocular pressure and endothelial cell morphometry did not changed significantly in long term postoperatively. Two eyes developed anterior cataract in 3a and 5a after the ICL implantation. There were no case developed pupillary block glaucoma.

    CONCLUSION: Posterior chamber ICL implantation was a safe and stable procedure for the correction of myopia and astigmatism.

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李红惠,李芳芳,张卉卉,等.有晶状体眼后房型人工晶状体植入矫正近视及散光的长期临床研究.国际眼科杂志, 2021,21(3):524-528.

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  • 收稿日期:2020-07-22
  • 最后修改日期:2021-01-26
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  • 在线发布日期: 2021-02-24
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