AIM:To comparatively analyze the results of ultra-wide-field fluorescein angiography and standard 7-field imaging in diabetic retinopathy(DR), so as to provide a basis for early diagnosis and treatment of the disease.

METHODS: A retrospective study was conducted. The clinical data of 120 patients with DR admitted to Tangshan Eye Hospital between June 2018 and June 2020 were collected. All patients were subjected to ultra-wide-field fluorescein angiography and standard 7-field imaging. Taking fundus examination results as the golden standard, the value of the two methods in differential diagnosis of fundus lesions and staging of DR was analyzed.

RESULTS: Compared with standard 7-field imaging, the retinal view area, retinal non-perfusion(NP)area, retinal neovascularization(NV)area, panretinal laser photocoagulation area and structure changes of macular arch observed by ultra-wide-field fluorescein angiography were significantly larger(P<0.05), and the graph obtaining time was significantly shorter(P<0.05). The accurate detection rate of DR by ultra-wide-field fluorescein angiography was 94.8%(165/174), significantly higher than 87.4%(152/174)by standard 7-field imaging(P<0.05).

CONCLUSION: Ultra-wide-field fluorescein angiography has more advantages over standard 7-field imaging in the diagnosis of DR, especially in the time and space of examination. Besides, the former can better display macular and optic disc lesions, which is conducive to evaluation of DR, thereby providing more reference for early diagnosis and treatment of DR.