Interleukin-17(IL-17)is an important pro-inflammatory factor in autoimmune diseases and many inflammatory diseases. Studies have shown IL-17 plays a vital role in the pathogenesis of eye disease. This paper reviews the function and mechanism of IL-17 in keratitis, dry eye, uveitis, diabetic retinopathy, and age-related macular degeneration, providing new ideas and targets for the treatment of these diseases.