High intraocular pressure is the most concerned complication of the implantation surgery of V4c implantable contact lens(ICL). According to the appearance time of intraocular pressure elevation, it can be divided into three periods: the early period(1wk after surgery), the middle period(1-4wk after surgery)and the late period(1-3mo after surgery). During the early period, the intraocular pressure increase is mainly caused by the residue of the intraoperative viscoelastic. In the middle period, the application of the hormone drugs results the elevation of the intraocular pressure. Furthermore, during the late period, persistent increasing of the intraocular pressure may cause the secondary glaucoma. Identifying the mechanism of different periods of intraocular pressure rise correctly and thus formulating a reasonable treatment plan, is of great significance for the prevention of glaucoma and other long-term vision threatening complications. Therefore, this article reviews the appearance time and mechanism of the intraocular pressure rise after surgery.