Myopic anisometropia is a special type of refractive error. As the prevalence of myopia has rapidly increased worldwide in recent years, the prevalence of myopic anisometropia is also growing year by year. Anisometropia can cause aniseikonia of the retinal and fusion impairment, leading the problems such as asthenopia, monocular suppression, amblyopia, and stereopsis disorder, which results in negative effects on patients' work and life. Therefore, it is crucial for children to discover myopic anisometropia in early stage and take effective measures in time to delay the progression of it. At present, a wide range of research has been conducted to study the methods that control the progression of myopia among children. It has been found that orthokeratology lens(OK lens)can effectively slow the progression of myopic anisometropia. This article mainly reviews the mechanism of how orthokeratology control myopic anisometropia, its effect on delaying the progression of myopic anisometropia, and its impact on stereopsis among children with myopic anisometropia, aiming to provide a theoretical basis for the prevention and control of myopic anisometropia in the future.