[关键词]
[摘要]
中心性浆液性脉络膜视网膜病变(CSC)是最早被描述的厚脉络膜疾病,以视物变形、视觉丧失为主要特征,常见于中年男性。研究表明CSC眼部的血流处于超负荷状态,表现为涡静脉壶腹和脉络膜大中血管的扩张,这种流出通道的阻滞和巩膜厚度存在一定的联系,脉络膜毛细血管也因受到大血管层的压迫而出现充盈缺损,随着时间的延长血管会发生重塑,静脉之间相互吻合以建立新的引流途径来缓解血流瘀滞,这些涡静脉和脉络膜血流的异常改变对理解CSC潜在的发病机制及其临床表现至关重要,在这篇综述中我们重点介绍了CSC涡静脉和脉络膜血流系统的改变,期望了解血流的变化如何影响CSC的病程,以及与治疗反应之间的联系,通过血流状态推断疾病所处阶段以便优化治疗策略,提高患者的预后。
[Key word]
[Abstract]
Central serous chorioretinopathy (CSC), the first described Pachychoroid disease, is characterized by visual distortions and loss of vision, which are commonly seen in middle-aged men. Research has demonstrated that ocular blood flow in CSC is in a state of overload, characterized by the dilation of vortex vein ampullae and choroidal vasculature. The obstruction of venous outflow is linked to scleral thickness, while the choriocapillaris exhibits perfusion deficits due to compression from the engorged vascular layer. Over time, vascular remodeling occurs, with venous anastomoses forming to create alternative drainage pathways and mitigate blood stasis. These abnormalities in vortex vein dynamics and choroidal circulation play a critical role in elucidating the underlying pathophysiology and clinical manifestations of CSC.This review highlights the alterations in vortex vein and choroidal vasculature in CSC, hoping to understand how how the changes of blood flow affect the course of CSC and their correlation with treatment response. By evaluating blood flow dynamics, we aim to determine the disease stage more accurately, optimize therapeutic strategies, and ultimately enhance patient outcomes.
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