目的：运用眼表综合分析仪Keratograph 5M、三维眼前节分析系统Pentacam、自动电脑验光仪KR.800、光学相干生物测量仪IOL Master及波前像差仪KR-1W五种不同仪器测量高龄人群白内障术前角膜曲率值，分析其差异性和一致性，为高龄人群白内障术前精确的计算人工晶体度数做参考。 方法：前瞻性研究。选取2022年10月至2024年11月在我院眼科就诊的高龄白内障患者53例90眼，对所有患者分别采用Keratograph 5M、Pentacam、KR.800、IOL Master、KR-1W测量术眼角膜曲率值（K1、K2），并计算出平均角膜曲率（mean keratometry，Km）。 结果：在测量K1、K2、Km值时，Keratograph 5M与Pentacam、IOL Master测量值的差异有统计学意义（P＜0.05），而Keratograph 5M与KR.800、KR-1W测量值的差异无统计学意义（P＞0.05）。经Pearson相关分析，其结果显示：Keratograph 5M与KR.800、Pentacam、IOL Master 、KR-1W测量值间均有一定相关性（r=0.913～0.987，P＜0.01）。Bland-Altman散点图中，显示Keratograph 5M与KR.800、KR-1W在测量角膜曲率值时一致性较好，与Pentacam、IOL Master的一致性较差。 结论：作为一种眼表综合分析仪，Keratograph 5M具有简单快捷、可重复性强、配合要求低等优点。在对高龄人群测量角膜曲率时，Keratograph 5M与KR.800、KR-1W一致性较好，可根据患者自身情况和配合程度相互替换，与Pentacam、IOL Master的一致性较差，使用中需结合临床使用意义及目的加以判断。

Abstract AIM: This study aims to provide a reference for preoperative keratometry assessment and accurate intraocular lens (IOL) power calculation in elderly cataract patients by analyzing the differences and consistency of corneal curvature measurements obtained from five different systems—Keratograph 5M, Pentacam, KR.800 autorefractor, IOL Master optical biometer, and KR-1W wavefront aberrometer. METHODS: This prospective study included 90 eyes from 53 elderly cataract in-patients who were admitted to our ophthalmology department between October 2022 and November 2024. The corneal curvature values (K1, K2) of post-operative eyes were measured using Keratograph 5M, Pentacam, KR.800, IOL Master, and KR-1W, and the mean keratometry (Km) was calculated. RESULTS: Statistically significant differences were observed in K1, K2, and Km values between Keratograph 5M and Pentacam, as well as between Keratograph 5M and IOL Master (P < 0.05), whereas no significant differences were found between Keratograph 5M and KR.800 or KR-1W (P > 0.05). Pearson correlation analysis showed a strong correlation of measurements obtained using Keratograph 5M with those from KR.800, Pentacam, IOL Master, and KR-1W (r = 0.913–0.987, P < 0.01). Bland-Altman scatter plots demonstrated good measurement consistency between Keratograph 5M and KR.800 or KR-1W, while its consistency with Pentacam and IOL Master was relatively poor. CONCLUSION: As an ocular surface analyzer, Keratograph 5M offers advantages such as simplicity, rapid measurement, strong repeatability, and low patient cooperation requirements. In elderly patients, corneal curvature measurements obtained using Keratograph 5M demonstrated good consistency with those from KR.800 and KR-1W, making them interchangeable based on individual conditions and cooperation levels of patients. However, its consistency with Pentacam and IOL Master was relatively poor; therefore, clinical significance and intended use should be considered when selecting such measurement devices.